Language:
  
[Sign in] [Register]   

EIAab logo

Index > Protein center > Cdt1(Gene name) > Mouse
  • Add your favorite
  • Cdt1 (Gene name),
  • DNA replication factor Cdt1 (Protein name ),  CDT1_MOUSE from NCBI database.
  • top
  • Come back to page head.
  • |
  • General Annotation
  • |
  • Antigen Annotation
  • |
  • 3D
  • |
  • Predicted Eptitope
  • |
  • Vaild Sequence
  • |
  • Related Databases
  • |
  • Feedback
  • Gene name:
    Cdt1(Ris2);
    Protein name:
    DNA replication factor Cdt1;
    Alternative:
    Retroviral insertion site 2 protein;Double parked homolog(DUP);
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with PCNA (By similarity). Interacts with GMNN; inhibits both binding of the MCM complex to origins of replication and DNA-binding activity.
    Function:
    Cooperates with CDC6 to promote the loading of the mini-chromosome maintenance complex onto chromatin to form the pre-replication complex necessary to initiate DNA replication. Binds DNA in a sequence-, strand-, and conformation-independent manner. Potential oncogene.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    557
    Sequence:
    50:
    MAQSRVTDFY | ACRRPGLTTP | RAKSICLTPS | PGGLVAPAFT | RSSSRKRARP | 
    100:
    PAEPGSDQPA | PLARRRLRLP | GLDSCPSSLP | EPSSPAEPSP | PADPSPPADP | 
    150:
    GSPVCPSPVK | RTKSTTVYVG | QQPGKIPSED | SVSELQSCLR | RARKLGAQAR | 
    200:
    ALRARVQENA | VEPSTPDAKV | PTEQPCVEKA | PAYQRFHALA | QPGLPGLVLP | 
    250:
    YKYQVLVEMF | RSMDTIVSML | HNRSETVTFA | KVKQGVQEMM | RKRFEERNVG | 
    300:
    QIKTVYPTSY | RFRQECNVPT | FKDSIKRSDY | QLTIEPLLGQ | EAGGATQLTA | 
    350:
    TCLLQRRQVF | RQNLVERVKE | QHKVFLASLN | PPMAVPDDQL | TRWHPRFNVD | 
    400:
    EVPDIEPAEL | PQPPVTEKLT | TAQEVLARAR | SLMTPKMEKA | LSNLALRSAE | 
    450:
    PGSPGTSTPP | LPATPPATPP | AASPSALKGV | SQALLERIRA | KEVQKQLARM | 
    500:
    TRCPEQELRL | QRLERLPELA | RVLRNVFVSE | RKPALTMEVV | CARMVDSCQT | 
    550:
    ALSPGEMEKH | LVLLAELLPD | WLSLHRIRTD | TYVKLDKAVD | LAGLTARLAH | 
    557:
    HVHAEGL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    String:
    Pfam:
    SMR:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse DNA replication factor Cdt1
    Cat.:
    E14045h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse DNA replication factor Cdt1
    Cat.:
    E14045m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse DNA replication factor Cdt1
    Cat.:
    U14045m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse DNA replication factor Cdt1
    Cat.:
    U14045h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    Polyclonal Antibody for Mouse DNA replication factor Cdt1
    Polyclonal Antibody for Mouse DNA replication factor Cdt1
    Monoclonal Antibody for Mouse DNA replication factor Cdt1
    Monoclonal Antibody for Mouse DNA replication factor Cdt1
    Protein for Mouse DNA replication factor Cdt1
    Protein for Mouse DNA replication factor Cdt1

    R&D Technical Data
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Precision
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Recovery
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Linearity
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "Oncogenic potential of the DNA replication licensing protein CDT1."
      Arentson E. , Faloon P. , Seo J. , Moon E. , Studts J.M. , Fremont D.H. , Choi K.
      Oncogene21:1150-1158(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA];FUNCTION;DEVELOPMENTAL STAGE
      strain: 129/Sv.
    2. 2.
      "Mouse geminin inhibits not only Cdt1-MCM6 interactions but also a novel intrinsic Cdt1 DNA binding activity."
      Yanagi K. , Mizuno T. , You Z. , Hanaoka F.
      J. Biol. Chem.277:40871-40880(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;DNA-BINDING;INTERACTION WITH GMNN; MCM6 AND ORC2L
    3. 3.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Embryonic stem cell.
      tissue: Fetal head.
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Mammary gland.
      tissue: Olfactory epithelium.
    5. 5.
      "Cdt1 phosphorylation by cyclin A-dependent kinases negatively regulates its function without affecting geminin binding."
      Sugimoto N. , Tatsumi Y. , Tsurumi T. , Matsukage A. , Kiyono T. , Nishitani H. , Fujita M.
      J. Biol. Chem.279:19691-19697(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;PHOSPHORYLATION;SUBCELLULAR LOCATION
    6. 6.
      "Structural basis for inhibition of the replication licensing factor Cdt1 by geminin."
      Lee C. , Hong B. , Choi J.M. , Kim Y. , Watanabe S. , Ishimi Y. , Enomoto T. , Tada S. , Kim Y. , Cho Y.
      Nature430:913-917(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.8 ANGSTROMS) OF 172-368;INTERACTION WITH GMNN
    Product Feedback Wall
    Hot Genes
    Atf2 ASPRO ACE ALCAM C19orf80 Trap1a Gdf5
    Top Searches
    Ubiquitin-protein ligase metalloproteinase Ubiquitin ELISA Alpha Tumor necrosis Asprosin TRAP1A
    Why choose EIAAB
    Our products have been quoted by many publications in famous journals such as Cell; Cell Metabolism; Hepatology; Biomaterials.more
    Further Information
    About us Protein center Bank account Distributors Terms & Conditions Career eiaab.com.cn

    Copyright & copy www.eiaab.com2006-2016 All Rights Reserved    EIAab         Email:eiaab@eiaab.com

    鄂ICP备10015095号-1

    鄂公网安备 42018502005535号

    Twitter